• Title Innovative approaches for diagnosing tuberculosis in the era of HIV
  • Granting Agency CIHR (Canadian Institutes of Health Sciences)
  • Period 1 Oct. 2008 – 30 Sept. 2011
  • Amount $319,198 CAD

This study was a 3-year study of new tests for the diagnosis of TB in Canada, India and South Africa.

Publications

Ling, Daphne I; Pai, Madhukar; Schiller, Ian; Dendukuri, Nandini

A Bayesian framework for estimating the incremental value of a diagnostic test in the absence of a gold standard (Journal Article)

In: BMC medical research methodology, vol. 14, no. 1, pp. 67, 2014.

(Links)

Nicolau, I; Ling, D; Tian, L; Lienhardt, C; Pai, M

Methodological and reporting quality of systematic reviews on tuberculosis (Journal Article)

In: The International Journal of Tuberculosis and Lung Disease, vol. 17, no. 9, pp. 1160–1169, 2013.

(Links)

Ling, Daphne I; Nicol, Mark P; Pai, Madhukar; Pienaar, Sandra; Dendukuri, Nandini; Zar, Heather J

Incremental value of T-SPOT. TB for diagnosis of active pulmonary tuberculosis in children in a high-burden setting: a multivariable analysis (Journal Article)

In: Thorax, vol. 68, no. 9, pp. 860–866, 2013.

(Links)

Ling, Daphne I; Crépeau, Claire A; Dufresne, Marieke; Khan, Shazia; Quach, Caroline; Dendukuri, Nandini; Schwartzman, Kevin; Menzies, Dick; Lands, Larry C; Pai, Madhukar

Evaluation of the impact of interferon-gamma release assays on the management of childhood tuberculosis (Journal Article)

In: The Pediatric Infectious Disease Journal, vol. 31, no. 12, pp. 1258–1262, 2012.

(Links)

Nicolau, Ioana; Tian, Lulu; Menzies, Dick; Ostiguy, Gaston; Pai, Madhukar

Point-of-care urine tests for smoking status and isoniazid treatment monitoring in adult patients (Journal Article)

In: PLoS One, vol. 7, no. 9, pp. e45913, 2012.

(Links)

Nicolau, Ioana; Ling, Daphne; Tian, Lulu; Lienhardt, Christian; Pai, Madhukar

Research questions and priorities for tuberculosis: a survey of published systematic reviews and meta-analyses (Journal Article)

In: PLoS One, vol. 7, no. 7, pp. e42479, 2012.

(Links)

Ling, Daphne I; Pai, Madhukar; Davids, Virginia; Brunet, Laurence; Lenders, Laura; Meldau, Richard; Calligaro, Gregory; Allwood, Brian; van Zyl-Smit, Richard; Peter, Jonny; others,

Are interferon-gamma release assays useful for diagnosing active tuberculosis in a high-burden setting? (Journal Article)

In: European Respiratory Journal, vol. 38, no. 3, pp. 649–656, 2011.

(Links)

Ling, Daphne I; Flores, Laura L; Riley, Lee W; Pai, Madhukar

Commercial nucleic-acid amplification tests for diagnosis of pulmonary tuberculosis in respiratory specimens: meta-analysis and meta-regression (Journal Article)

In: PLoS One, vol. 3, no. 2, pp. e1536, 2008.

(Links)