First project

  • Title Validation of interferon-gamma assay for the diagnosis of tuberculosis infection in health care workers
  • Granting Agency CIHR (Canadian Institutes of Health Sciences)
  • Period 1 Oct. 2006 – 30 Sept. 2009
  • Amount $249,285 CAD

This study was a 3-year cohort study of new in-vitro tests for the diagnosis of latent TB infection among healthcare workers in Montreal and India.

Second project

  • Title Tuberculosis screening of health care workers: do novel blood tests have a role?
  • Granting Agency CIHR (Canadian Institutes of Health Sciences)
  • Period 1 Oct. 2009 – 30 Sept. 2012
  • Amount $336,725 CAD

This study was the continuation of a cohort study of new in-vitro tests for the diagnosis of latent TB infection among healthcare workers in Montreal and India.

Publications

Zwerling, Alice; Pai, Madhukar; Michael, Joy Sarojini; Christopher, Devasahayam J

Serial testing using interferon-gamma release assays in nursing students in India (Journal Article)

In: European Respiratory Journal, vol. 44, no. 1, pp. 257–260, 2014.

(Links)

Zwerling, Alice; Joshi, Rajnish; Kalantri, SP; Dakshinamoorthy, Gajalakshmi; Reddy, Maryada Venkatarama; Benedetti, Andrea; Schwartzman, Kevin; Menzies, Dick; Pai, Madhukar

Trajectories of tuberculosis-specific interferon-gamma release assay responses among medical and nursing students in rural India (Journal Article)

In: Journal of Epidemiology and Global Health, vol. 3, no. 2, pp. 105–117, 2013.

(Links)

Zwerling, Alice; Benedetti, Andrea; Cojocariu, Mihaela; McIntosh, Fiona; Pietrangelo, Filomena; Behr, Marcel A; Schwartzman, Kevin; Menzies, Dick; Pai, Madhukar

Repeat IGRA testing in Canadian health workers: conversions or unexplained variability? (Journal Article)

In: PLoS One, vol. 8, no. 1, pp. e54748, 2013.

(Links)

Zwerling, Alice; Cojocariu, Mihaela; McIntosh, Fiona; Pietrangelo, Filomena; Behr, Marcel A; Schwartzman, Kevin; Benedetti, Andrea; Dendukuri, Nandini; Menzies, Dick; Pai, Madhukar

TB screening in Canadian health care workers using interferon-gamma release assays (Journal Article)

In: PLoS One, vol. 7, no. 8, pp. e43014, 2012.

(Links)

Joshi, R; Narang, U; Zwerling, A; Jain, D; Jain, V; Kalantri, S; Pai, M

Predictive value of latent tuberculosis tests in Indian healthcare workers: a cohort study (Journal Article)

In: European Respiratory Journal, vol. 38, no. 6, pp. 1475–1477, 2011.

(Links)

Christopher, Devasahayam J; James, Prince; Daley, Peter; Armstrong, Lois; Isaac, Barney TJ; Thangakunam, Balamugesh; Premkumar, Beulah; Zwerling, Alice; Pai, Madhukar

High annual risk of tuberculosis infection among nursing students in South India: a cohort study (Journal Article)

In: PLoS One, vol. 6, no. 10, pp. e26199, 2011.

(Links)

Zwerling, Alice; van den Hof, Susan; Scholten, Jerod; Cobelens, Frank; Menzies, Dick; Pai, Madhukar

Interferon-gamma release assays for tuberculosis screening of healthcare workers: a systematic review (Journal Article)

In: Thorax, vol. 67, pp. 62-70, 2011.

(Links)

Christopher, Devasahayam J; Daley, Peter; Armstrong, Lois; James, Prince; Gupta, Richa; Premkumar, Beulah; Michael, Joy Sarojini; Radha, Vedha; Zwerling, Alice; Schiller, Ian; others,

Tuberculosis infection among young nursing trainees in South India (Journal Article)

In: PLoS One, vol. 5, no. 4, pp. e10408, 2010.

(Links)